Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.60 |
| ▸ | RELA | Q04206 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7138301 | 0.89 | CYP19A1 (0.67) | CYP19A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL5654351 | 0.83 | ALDH1A1 (0.47) | CYP19A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL5759428 | 0.82 | SMN1; SMN2 (0.79) | SMN1; SMN2LMNANPC1RAB9ATP53 | |
| SCHEMBL31415781 | 0.82 | CYP19A1 (0.54) | CYP19A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL24041752 | 0.81 | LMNA (0.71) | SMN1; SMN2LMNANPC1RAB9ATP53 | |
| SCHEMBL23609486 | 0.81 | LMNA (0.49) | CYP19A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL8545347 | 0.80 | SIGMAR1 (0.53) | SIGMAR1 | |
| SCHEMBL23861179 | 0.79 | CYP19A1 (0.54) | CYP19A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL30927861 | 0.78 | MEN1 (0.62) | CYP19A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL5759143 | 0.78 | ALDH1A1 (0.52) | CYP19A1SMN1; SMN2LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040133008-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-08 | — | — | US | disclosed |
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |
| EP-0023637-B1 | SUBSTITUTED 2,3-DIHYDROBENZOFURYLMETHYL-CYCLOPROPANECARBOXYLIC ACID ESTERS, PROCESS FOR THEIR PREPARATION, PROCESS FOR COMBATTING PARASITES, AND AGENTS THEREFOR | BASF Aktiengesellschaft (DE) | 1984-04-04 | — | — | EP | disclosed |
| US-4344961-A | MITICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1982-08-17 | — | — | US | disclosed |
| US-4315017-A | Triazole derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1982-02-09 | — | — | US | disclosed |
| US-4298615-A | INSECTICIDES, MITICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1981-11-03 | — | — | US | disclosed |
| EP-0008651-B1 | DERIVATIVES OF TRIAZOLE, PROCESS FOR THEIR PRODUCTION AND INSECTICIDES CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1981-10-14 | — | — | EP | disclosed |
| EP-0023637-A1 | Substituted 2,3-dihydrobenzofurylmethyl-cyclopropanecarboxylic acid esters, process for their preparation, process for combatting parasites, and agents therefor | BASF Aktiengesellschaft (DE) | 1981-02-11 | — | — | EP | disclosed |
| EP-0012273-A1 | Carboxylic acid esters, process for their preparation and their use as pesticides | BASF Aktiengesellschaft (DE) | 1980-06-25 | — | — | EP | disclosed |
| EP-0008651-A1 | Derivatives of triazole, process for their production and insecticides containing them | BASF Aktiengesellschaft (DE) | 1980-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040133008-A1 | Amide compounds | APOB, APOL1, LDLR | CYP19A1 860/4885SMN1; SMN2 1836/4885LMNA 1410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.