Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | SRC | P12931 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22995644 | 0.79 | NPSR1 (0.47) | NPSR1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL23609005 | 0.78 | CSNK2A2 (0.36) | NPSR1ALDH1A1MAPTMEN1KMT2A | |
| Diphenylamine SCHEMBL5223111 | 0.75 | MAPT (0.47) | NPSR1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL23609704 | 0.75 | LTA4H (0.38) | NPSR1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL13308526 | 0.70 | HPGD (0.58) | NPSR1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4639004 | 0.70 | HPGD (0.58) | NPSR1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL29416259 | 0.70 | HPGD (0.58) | NPSR1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL23609098 | 0.70 | ALDH1A1 (0.36) | NPSR1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1851950 | 0.70 | ALDH1A1 (0.62) | ALDH1A1MAPTMEN1KMT2AAR | |
| SCHEMBL23567608 | 0.70 | HPGD (0.52) | NPSR1ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021133689-A2 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-07-01 | — | — | WO | disclosed |