Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29974565 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MAPTATMLMNAHSP90AA1 | |
| SCHEMBL29972895 | 0.82 | MAPT (0.58) | ALDH1A1MAPTATMLMNAHSP90AA1 | |
| SCHEMBL28852575 | 0.81 | RAB9A (0.49) | ALDH1A1MAPTATMLMNAHSP90AA1 | |
| SCHEMBL23609099 | 0.81 | RAB9A (0.49) | ALDH1A1MAPTATMLMNAHSP90AA1 | |
| SCHEMBL28376851 | 0.77 | MAPT (0.67) | ALDH1A1MAPTATMLMNAHSP90AA1 | |
| SCHEMBL29975094 | 0.74 | NR3C1 (0.40) | ALDH1A1MAPTLMNASTAT3L3MBTL1 | |
| SCHEMBL23609105 | 0.74 | NR3C1 (0.40) | ALDH1A1MAPTLMNASTAT3L3MBTL1 | |
| SCHEMBL31339796 | 0.73 | ERN1 (0.50) | ALDH1A1MAPTATMLMNAHSP90AA1 | |
| SCHEMBL1619153 | 0.73 | ERN1 (0.50) | ALDH1A1MAPTATMLMNAHSP90AA1 | |
| SCHEMBL3060879 | 0.71 | ALDH1A1 (0.43) | ALDH1A1MAPTATMLMNAHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021133689-A2 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-07-01 | — | — | WO | disclosed |