Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 19/20 | 0.59 |
| ▸ | PIM1 | P11309 | 1/20 | 0.52 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.52 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.52 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.52 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3796104 | 0.88 | PTGES (0.48) | PTGESPIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL2361393 | 0.84 | PTGES (0.47) | PTGESPIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL2361320 | 0.84 | PTGES (0.47) | PTGESJAK2 | |
| SCHEMBL2361981 | 0.81 | PTGES (0.44) | PTGESPIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL2360991 | 0.81 | RHEB (0.52) | PTGESJAK2 | |
| SCHEMBL13405914 | 0.80 | RHEB (0.54) | PTGESJAK2 | |
| SCHEMBL2360771 | 0.80 | PTGES (0.50) | PTGESJAK2 | |
| SCHEMBL2361762 | 0.79 | F10 (0.54) | PTGES | |
| SCHEMBL2361558 | 0.79 | PTGES (0.53) | PTGESJAK2 | |
| SCHEMBL2361014 | 0.79 | PTGES (0.43) | PTGESJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011099832-A2 | NOVEL BENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CRYSTALGENOMICS, INC. (KR) | 2011-08-18 | — | — | WO | disclosed |
| WO-2011099832-A2 | NOVEL BENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CRYSTALGENOMICS, INC. (KR) | 2011-08-18 | — | — | WO | disclosed |