Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5282910 | 0.77 | CYP3A4 (0.37) | CYP3A4TDP1TSHRMAPTCACNA1B | |
| SCHEMBL2327749 | 0.76 | MMP8 (0.36) | CYP3A4TSHR | |
| SCHEMBL7822624 | 0.76 | MAPT (0.42) | CYP3A4TDP1TSHRMAPTCACNA1B | |
| SCHEMBL7822619 | 0.76 | CYP3A4 (0.36) | CYP3A4TDP1TSHRMAPTCACNA1B | |
| SCHEMBL2364280 | 0.75 | CYP3A4 (0.38) | CYP3A4TDP1TSHRMAPTCACNA1B | |
| SCHEMBL8586425 | 0.75 | CYP3A4 (0.38) | CYP3A4TDP1TSHRMAPTCACNA1B | |
| SCHEMBL7094910 | 0.74 | CYP3A4 (0.41) | CYP3A4TDP1TSHRMAPTCACNA1B | |
| SCHEMBL11384805 | 0.74 | CYP3A4 (0.35) | CYP3A4TDP1TSHRMAPTCACNA1B | |
| SCHEMBL3407885 | 0.73 | TSHR (0.36) | CYP3A4TDP1TSHRMAPTCACNA1B | |
| Ammonia Solution, Strong SCHEMBL10836805 | 0.72 | CYP3A4 (0.39) | CYP3A4TDP1TSHRMAPTCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060149091-A1 | Method for producing difluoro-acetyl-acetic acid alkylesters | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-07-06 | — | — | US | claimed |
| EP-1644314-B1 | METHOD FOR PRODUCING DIFLUORO-ACETYL-ACETIC ACID ALKYLESTERS | BAYER CROPSCIENCE AG (DE) | 2011-08-10 | — | — | EP | disclosed |
| US-7585998-B2 | Method for producing difluoro-acetyl-acetic acid alkylesters | BAYER CROPSCIENCE AG (DE) | 2009-09-08 | — | — | US | disclosed |
| US-20060149091-A1 | Method for producing difluoro-acetyl-acetic acid alkylesters | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-07-06 | — | — | US | disclosed |
| EP-1644314-A1 | METHOD FOR PRODUCING DIFLUORO-ACETYL-ACETIC ACID ALKYLESTERS | Bayer CropScience Aktiengesellschaft (DE) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005003077-A1 | METHOD FOR PRODUCING DIFLUORO-ACETYL-ACETIC ACID ALKYLESTERS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060149091-A1 | Method for producing difluoro-acetyl-acetic acid alkylesters | APEH, ACACA, NAT1 | CYP3A4 343/4885TDP1 1757/4885TSHR 1158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.