Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14780291 | 0.86 | CA9 (0.41) | CA9CA12CA1ALDH1A1STAT3 | |
| SCHEMBL14827580 | 0.86 | CA9 (0.43) | CA9CA12CA1ALDH1A1STAT3 | |
| SCHEMBL922407 | 0.86 | ALDH1A1 (0.53) | CA9CA12CA1ALDH1A1STAT3 | |
| SCHEMBL18644929 | 0.86 | ALDH1A1 (0.53) | CA9CA12CA1ALDH1A1STAT3 | |
| SCHEMBL12865316 | 0.86 | ALDH1A1 (0.53) | CA9CA12CA1ALDH1A1STAT3 | |
| SCHEMBL18613994 | 0.86 | ALDH1A1 (0.53) | CA9CA12CA1ALDH1A1STAT3 | |
| SCHEMBL478342 | 0.86 | ALDH1A1 (0.53) | CA9CA12CA1ALDH1A1STAT3 | |
| SCHEMBL4379133 | 0.86 | ALDH1A1 (0.53) | CA9CA12CA1ALDH1A1STAT3 | |
| SCHEMBL881292 | 0.86 | ALDH1A1 (0.53) | CA9CA12CA1ALDH1A1STAT3 | |
| SCHEMBL1145153 | 0.86 | ALDH1A1 (0.53) | CA9CA12CA1ALDH1A1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230098686-A1 | NERVE SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | UNIV OREGON HEALTH & SCIENCE (US) | 2023-03-30 | — | — | US | disclosed |
| US-20230098438-A1 | OXAZINE-BASED WATER-SOLUBLE FLUOROPHORE COMPOUNDS FOR IN VIVO NERVE IMAGING | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2023-03-30 | — | — | US | disclosed |
| EP-4084829-A1 | OXAZINE-BASED WATER-SOLUBLE FLUOROPHORE COMPOUNDS FOR IN VIVO NERVE IMAGING | Oregon Health & Science University (US) | 2022-11-09 | — | — | EP | disclosed |
| WO-2021158820-A1 | NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-08-12 | — | — | WO | disclosed |
| WO-2021138116-A1 | OXAZINE-BASED WATER-SOLUBLE FLUOROPHORE COMPOUNDS FOR IN VIVO NERVE IMAGING | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230098438-A1 | OXAZINE-BASED WATER-SOLUBLE FLUOROPHORE COMPOUNDS FOR IN VIVO NERVE IMAGING | GAP43, NTRK1, MAG | CA9 3156/4885CA12 2344/4885CA1 1882/4885 |
| US-20230098686-A1 | NERVE SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | PFAS, NPFFR2, NPFFR1 | CA9 2099/4885CA12 2687/4885CA1 3277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.