Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PRKACA | P17612 | 5/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 5/20 | 0.45 |
| ▸ | IDH1 | O75874 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 4/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.39 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.36 |
| ▸ | CDK9 | P50750 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2027616 | 0.82 | PRKACA (0.60) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL2361800 | 0.81 | KDM4E (0.49) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL2031496 | 0.78 | KDM4E (0.45) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL1926108 | 0.77 | ALDH1A1 (0.47) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL2033557 | 0.73 | PRKACA (0.53) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL2362031 | 0.73 | TP53 (0.49) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL2033562 | 0.73 | PRKACA (0.53) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL2365574 | 0.73 | ALOX15 (0.39) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL4565790 | 0.72 | PRKACA (0.54) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL2361255 | 0.72 | HTR2B (0.51) | KDM4EALDH1A1MAPTGFERTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011099832-A2 | NOVEL BENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CRYSTALGENOMICS, INC. (KR) | 2011-08-18 | — | — | WO | disclosed |