Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22777966 | 0.74 | NPC1 (0.38) | MEN1ALDH1A1KMT2A | |
| SCHEMBL23623186 | 0.70 | SIRT2 (0.45) | — | |
| SCHEMBL23612201 | 0.69 | LMNA (0.39) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL24664744 | 0.68 | CHRNB2 (0.37) | ALDH1A1 | |
| SCHEMBL22778039 | 0.67 | CHRNB2 (0.37) | CRBNALDH1A1MAPT | |
| SCHEMBL22777936 | 0.67 | KDM1A (0.51) | — | |
| SCHEMBL29714440 | 0.67 | KDM1A (0.51) | — | |
| SCHEMBL5592090 | 0.67 | MGLL (0.53) | ALDH1A1MAPT | |
| SCHEMBL22803789 | 0.65 | ESR1 (0.49) | — | |
| SCHEMBL15280136 | 0.63 | SYK (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4085061-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM Due, Inc. (US) | 2022-11-09 | — | — | EP | disclosed |
| WO-2021138419-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC, (US) | 2021-07-08 | — | — | WO | disclosed |