Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20488746 | 0.88 | ACHE (0.35) | MGLL | |
| SCHEMBL29855032 | 0.77 | DYRK1A (0.37) | — | |
| SCHEMBL23613363 | 0.76 | BRD4 (0.36) | ALDH1A1 | |
| SCHEMBL20487920 | 0.73 | CA12 (0.38) | HSD17B10 | |
| SCHEMBL25096528 | 0.73 | CFD (0.43) | — | |
| SCHEMBL20487852 | 0.71 | HPGD (0.38) | ALDH1A1 | |
| SCHEMBL25097625 | 0.70 | HSD17B10 (0.39) | ALDH1A1HSD17B10 | |
| SCHEMBL11668425 | 0.70 | MGLL (0.77) | MGLL | |
| SCHEMBL20488379 | 0.69 | QPCT (0.42) | ALDH1A1 | |
| SCHEMBL25097492 | 0.69 | HSD17B10 (0.34) | ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718626-B2 | Macrocyclic compounds for treatment of medical disorders | ACHILLION PHARMACEUTICALS, INC. (US) | 2023-08-08 | — | — | US | disclosed |
| US-11053253-B2 | Macrocyclic compounds for treatment of medical disorders | ACHILLION PHARMACEUTICALS, INC. (US) | 2021-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718626-B2 | Macrocyclic compounds for treatment of medical disorders | CFD, TFPI, CFH | MGLL 3086/4885ALDH1A1 3904/4885HSD17B10 2328/4885 |
| US-11053253-B2 | Macrocyclic compounds for treatment of medical disorders | CFD, TFPI, CFH | MGLL 3086/4885ALDH1A1 3904/4885HSD17B10 2328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.