SCHEMBL23614560

SCHEMBL23614560

BrC1C=C(c2ccccc2)CCC1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 1/20 0.33
SLC18A3 Q16572 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
ALDH1A1 P00352 3/20 0.32
MAPK1 P28482 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
CHRNB4 P30926 1/20 0.31
CHRNA3 P32297 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
HRH2 P25021 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31146753 0.75 SLC18A3 (0.39) SLC18A3ALDH1A1ALOX15TSHRCHRNB4
SCHEMBL29248293 0.75 ALDH1A1 (0.35) SLC18A3ALDH1A1ALOX15TSHRCHRNB4
SCHEMBL8187300 0.75 SLC18A3 (0.39) SLC18A3ALDH1A1ALOX15TSHRCHRNB4
SCHEMBL11517610 0.71 SLC18A3 (0.33) SLC18A3
SCHEMBL23532516 0.71 HRH2 (0.35) CYP11B2CHRNB4CHRNA3HRH2HRH3
SCHEMBL24228853 0.71 JAK2 (0.35) SLC18A3ALDH1A1HRH2HRH3
SCHEMBL4607832 0.68 ALDH1A1 (0.33) ALDH1A1MAPK1ALOX15TSHRCHRNB4
SCHEMBL11511662 0.67 L3MBTL1 (0.39) ALDH1A1TSHRGAA
SCHEMBL10981555 0.65 SMN1; SMN2 (0.35) ALDH1A1
SCHEMBL733324 0.65 SLC18A3 (0.38) SLC18A3ALDH1A1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3845522-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC DEVICE Shaanxi Lighte Optoelectronics Material Co., Ltd. (CN) 2021-07-07 EP disclosed