Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28795626 | 0.90 | KDM4E (0.38) | SMN1; SMN2TP53CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL23527397 | 0.88 | CYP3A4 (0.46) | SMN1; SMN2TP53CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL28362271 | 0.83 | MEN1 (0.43) | SMN1; SMN2TP53CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL29853701 | 0.80 | KDM4E (0.38) | SMN1; SMN2TP53CYP3A4KDM4EALDH1A1 | |
| SCHEMBL2149073 | 0.80 | KDM4E (0.38) | SMN1; SMN2TP53CYP3A4KDM4EALDH1A1 | |
| SCHEMBL2361528 | 0.78 | KDM4E (0.37) | SMN1; SMN2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL3800938 | 0.76 | KDM4E (0.36) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL7195959 | 0.74 | CYP1A2 (0.40) | CYP1A2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL7192168 | 0.74 | CYP1A2 (0.36) | TP53CYP3A4CYP1A2HIF1AKDM4E | |
| SCHEMBL8743877 | 0.74 | TP53 (0.40) | SMN1; SMN2TP53CYP3A4CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6534595-B2 | Blend of thermosetting resin, decomposable resin and solvent | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-03-18 | — | — | US | disclosed |
| US-20010038887-A1 | Coating solution for forming porous organic film | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-11-08 | — | — | US | disclosed |