Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25674461 | 1.00 | MMP2 (0.61) | MMP2NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL14295054 | 0.87 | SMN1; SMN2 (0.61) | NPC1RAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL17231646 | 0.83 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2LMNAKMT2A | |
| SCHEMBL19293154 | 0.83 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2LMNAKMT2A | |
| SCHEMBL11648896 | 0.83 | ITGB3 (0.69) | MMP2ITGB3ITGA2B | |
| SCHEMBL14345777 | 0.82 | NPC1 (0.69) | MMP2NPC1RAB9ALMNAKMT2A | |
| SCHEMBL13956896 | 0.81 | HDAC3 (0.58) | MMP2ITGB3ITGA2BHDAC3HDAC4 | |
| SCHEMBL8863136 | 0.81 | MMP2 (0.59) | MMP2ITGB3ITGA2BHDAC3HDAC4 | |
| SCHEMBL22331980 | 0.80 | RAB9A (0.67) | NPC1RAB9ASMN1; SMN2LMNAKMT2A | |
| SCHEMBL3456224 | 0.80 | RAB9A (0.67) | NPC1RAB9ASMN1; SMN2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4098248-A1 | ORAL SOLUTIONS COMPRISING LISDEXAMFETAMINE SALTS | LABOMED PHARMACEUTICAL COMPANY S.A. (GR) | 2022-12-07 | — | — | EP | disclosed |
| WO-2021136602-A1 | ORAL SOLUTIONS COMPRISING LISDEXAMFETAMINE SALTS | LABOSERVE PHARMACEUTICAL COMPANY S.A. (GR) | 2021-07-08 | — | — | WO | disclosed |
| EP-3845215-A1 | ORAL SOLUTIONS COMPRISING LISDEXAMFETAMINE SALTS | Laboserve Pharmaceutical Company S.A. (GR) | 2021-07-07 | — | — | EP | disclosed |