Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL339335 | 0.78 | ADORA2B (0.41) | CNR2 | |
| SCHEMBL12809034 | 0.74 | KDM4E (0.46) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL21941663 | 0.73 | TLR7 (0.46) | — | |
| SCHEMBL19935237 | 0.73 | KDM4E (0.34) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL21942000 | 0.70 | PIK3CA (0.32) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL23615487 | 0.69 | FGFR1 (0.32) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL6974701 | 0.68 | TLR7 (0.41) | — | |
| SCHEMBL338747 | 0.67 | L3MBTL1 (0.51) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL338592 | 0.66 | EGFR (0.30) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL338669 | 0.66 | AHCY (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3845227-A1 | COMBINED TREATMENT WITH A TLR7 AGONIST AND AN HBV CAPSID ASSEMBLY INHIBITOR | F. Hoffmann-La Roche AG (CH) | 2021-07-07 | — | — | EP | disclosed |