Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | GLP1R | P43220 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24771867 | 0.86 | PIN1 (0.36) | PGK1ALDH1A1VCAM1MAPTGAA | |
| SCHEMBL21136767 | 0.82 | PGK1 (0.38) | PGK1ALDH1A1VCAM1MAPTSMN1; SMN2 | |
| SCHEMBL21050688 | 0.79 | MAPT (0.37) | PGK1ALDH1A1VCAM1MAPTSMN1; SMN2 | |
| SCHEMBL4712057 | 0.79 | EGFR (0.39) | PGK1ALDH1A1VCAM1MAPTSMN1; SMN2 | |
| SCHEMBL2246959 | 0.79 | TP53 (0.39) | PGK1ALDH1A1VCAM1MAPTSMN1; SMN2 | |
| SCHEMBL21050767 | 0.77 | MAPT (0.37) | ALDH1A1VCAM1MAPTSMN1; SMN2LMNA | |
| SCHEMBL18249938 | 0.76 | BRD4 (0.40) | — | |
| SCHEMBL246700 | 0.75 | PDGFRB (0.49) | ALDH1A1MAPTPIN1 | |
| SCHEMBL29744240 | 0.75 | PDGFRB (0.49) | ALDH1A1MAPTPIN1 | |
| SCHEMBL29969235 | 0.74 | CYP1A2 (0.37) | ALDH1A1MAPTGAASMN1; SMN2PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3845532-B1 | QUINOLINO-PYRROLIDIN-2-ONE DERIVATIVE AND APPLICATION THEREOF | MEDSHINE DISCOVERY INC (CN) | 2022-12-21 | — | — | EP | disclosed |
| EP-3845532-A1 | QUINOLINO-PYRROLIDIN-2-ONE DERIVATIVE AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2021-07-07 | — | — | EP | disclosed |