Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.40 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.38 |
| ▸ | FPR3 | P25089 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23607906 | 0.83 | HDAC1 (0.44) | NR1H4ROCK1MCHR1HDAC1HDAC6 | |
| SCHEMBL23607855 | 0.79 | ROCK1 (0.44) | MAPTTP53ROCK1KCNQ4KCNQ5 | |
| SCHEMBL24329996 | 0.79 | TMEM97 (0.48) | CTSSCTSKFPR3FPR2CKS1B | |
| SCHEMBL17532689 | 0.79 | HPGD (0.46) | MAPTPARP1HDAC1HDAC3HDAC2 | |
| SCHEMBL13237 | 0.77 | CA14 (0.47) | GAACTSSCTSKHDAC1HDAC3 | |
| SCHEMBL14078350 | 0.77 | TRPM8 (0.49) | LPAR1LPAR5 | |
| SCHEMBL1065312 | 0.76 | CA2 (0.55) | MAPTCTSSCTSKFPR3FPR2 | |
| SCHEMBL14326995 | 0.76 | CA2 (0.55) | POLBGAACTSSCTSKFPR2 | |
| SCHEMBL14078301 | 0.76 | LPAR1 (0.43) | PARP1LPAR1LPAR5 | |
| SCHEMBL14078308 | 0.76 | TRPM8 (0.50) | POLBLPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3845276-B1 | BETA-AMINO ACID DERIVATIVE, KINASE INHIBITOR AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THE SAME | IND TECH RES INST (TW) | 2025-01-29 | — | — | EP | disclosed |
| US-11608319-B2 | Beta-amino acid derivative, kinase inhibitor and pharmaceutical composition containing the same, and method for performing an in vivo related application that benefits from the inhibition of a kinase | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2023-03-21 | — | — | US | disclosed |
| US-20220363645-A1 | BETA-AMINO ACID DERIVATIVE, KINASE INHIBITOR AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND METHOD FOR PERFORMING AN IN VIVO RELATED APPLICATION THAT BENEFITS FROM THE INHIBITION OF A KINASE | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2022-11-17 | — | — | US | disclosed |
| EP-3845276-A1 | SS-AMINO ACID DERIVATIVE, KINASE INHIBITOR AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THE SAME | Industrial Technology Research Institute (TW) | 2021-07-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11608319-B2 | Beta-amino acid derivative, kinase inhibitor and pharmaceutical composition containing the same, and method for performing an in vivo related application that benefits from the inhibition of a kinase | CSNK1A1, CSNK1D, CSNK1G3 | MAPT 3096/4885TP53 1577/4885NR1H4 1345/4885 |
| US-20220363645-A1 | BETA-AMINO ACID DERIVATIVE, KINASE INHIBITOR AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND METHOD FOR PERFORMING AN IN VIVO RELATED APPLICATION THAT BENEFITS FROM THE INHIBITION OF A KINASE | CSNK1A1, CSNK1D, CSNK1G3 | MAPT 3096/4885TP53 1577/4885NR1H4 1345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.