Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.67 |
| ▸ | CTSK | P43235 | 3/20 | 0.67 |
| ▸ | REN | P00797 | 8/20 | 0.53 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23616295 | 1.00 | CTSS (0.67) | CTSSCTSKRENCTSLCTSB | |
| SCHEMBL17706115 | 0.90 | CTSS (0.65) | CTSSCTSKRENCTSL | |
| SCHEMBL15635321 | 0.90 | CTSS (0.65) | CTSSCTSKRENCTSL | |
| SCHEMBL15635322 | 0.90 | CTSS (0.65) | CTSSCTSKRENCTSL | |
| SCHEMBL21367422 | 0.89 | CTSK (0.64) | CTSSCTSKRENCTSLCTSB | |
| SCHEMBL17452195 | 0.88 | CTSS (0.63) | CTSSCTSKRENCTSLCTSB | |
| SCHEMBL21219323 | 0.87 | REN (0.68) | CTSSCTSKRENCTSLCTSB | |
| SCHEMBL4374188 | 0.87 | CTSS (0.74) | CTSSCTSKCTSLCTSBSCN9A | |
| SCHEMBL18661099 | 0.87 | CTSS (0.74) | CTSSCTSKCTSLCTSBSCN9A | |
| SCHEMBL4365866 | 0.87 | CTSS (0.74) | CTSSCTSKCTSLCTSBSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3297678-B1 | AN IMPROVED PROCESSES FOR THE PREPARATION OF CARFILZOMIB OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | LAURUS LABS LTD (IN) | 2021-07-07 | — | — | EP | disclosed |