Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23616662 | 0.79 | KMT2A (0.37) | KMT2AMEN1CYP1A2MAPK8MAPK10 | |
| SCHEMBL8060939 | 0.78 | KMT2A (0.41) | KMT2AMEN1CYP1A2RAB9ANPC1 | |
| SCHEMBL14389813 | 0.77 | CYP4F2 (0.40) | KMT2AMEN1CYP1A2RAB9ANPC1 | |
| SCHEMBL8145953 | 0.76 | ALDH1A1 (0.44) | KMT2AMEN1CYP1A2RAB9ANPC1 | |
| SCHEMBL1295475 | 0.76 | ALOX5 (0.47) | KMT2AMEN1CYP1A2RAB9ANPC1 | |
| SCHEMBL5196465 | 0.76 | MAPK8 (0.31) | MAPK8MAPK10MAPK9PKMABCC1 | |
| SCHEMBL13225707 | 0.75 | NPC1 (0.42) | KMT2AMEN1CYP1A2RAB9ANPC1 | |
| SCHEMBL20561794 | 0.75 | KMT2A (0.41) | KMT2AMEN1CYP1A2RAB9ANPC1 | |
| SCHEMBL9925396 | 0.75 | KMT2A (0.41) | KMT2AMEN1CYP1A2RAB9ANPC1 | |
| SCHEMBL9925412 | 0.75 | ALDH1A1 (0.46) | KMT2AMEN1CYP1A2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3687506-B1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARM INC (US) | 2021-07-07 | — | — | EP | disclosed |