Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 2/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | KDM6B | O15054 | 1/20 | 0.30 |
| ▸ | KDM4A | O75164 | 1/20 | 0.30 |
| ▸ | KDM5C | P41229 | 1/20 | 0.30 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.30 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.30 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5198536 | 0.86 | MAPK8 (0.32) | MAPK8MAPK10MAPK9 | |
| SCHEMBL23616663 | 0.76 | KMT2A (0.38) | MAPK8MAPK10PKMMAPK9ABCC1 | |
| SCHEMBL6691461 | 0.63 | ALDH1A1 (0.36) | PKMABCC1 | |
| SCHEMBL9410725 | 0.63 | NPC1 (0.59) | MAPK8MAPK10PKMKDM4EMAPK9 | |
| SCHEMBL7354141 | 0.63 | USP2 (0.46) | KDM4E | |
| SCHEMBL6580043 | 0.62 | TDP1 (0.43) | KDM4E | |
| SCHEMBL5196821 | 0.60 | FFAR1 (0.48) | — | |
| SCHEMBL5197745 | 0.60 | JAK3 (0.39) | — | |
| SCHEMBL5196658 | 0.59 | MAPK8 (0.39) | MAPK8MAPK10KDM4EKDM6BKDM4A | |
| SCHEMBL5283509 | 0.59 | ALOX5 (0.40) | KDM4EKDM6BKDM4AKDM5CKDM4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1868983-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE 1-SUBSTITUTED-3-AMINOALCOHOLS | LONZA AG (CH) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006087166-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE 1-SUBSTITUTED-3-AMINOALCOHOLS | LONZA AG (CH) | 2006-08-24 | — | — | WO | disclosed |