Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 3/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9903771 | 0.81 | MAPT (0.48) | XDHSLC22A12ACVR1MEN1KMT2A | |
| SCHEMBL5987785 | 0.79 | TTR (0.47) | XDHSLC22A12ACVR1MEN1KMT2A | |
| SCHEMBL23616996 | 0.77 | KDM4E (0.32) | XDHSLC22A12KDM4EMAPTHSD17B10 | |
| SCHEMBL10577195 | 0.76 | SLC22A12 (0.59) | XDHSLC22A12MEN1KMT2AKEAP1 | |
| SCHEMBL19438782 | 0.75 | PTGS2 (0.53) | XDHSLC22A12ACVR1KDM4EHSD17B10 | |
| SCHEMBL12096314 | 0.72 | KDM4E (0.57) | XDHSLC22A12ACVR1MEN1KMT2A | |
| SCHEMBL31056099 | 0.71 | SLC22A12 (0.39) | XDHSLC22A12ACVR1KDM4EPOLB | |
| SCHEMBL10576768 | 0.69 | GPR35 (0.46) | XDHSLC22A12MEN1KMT2AKDM4E | |
| SCHEMBL23617163 | 0.69 | KDM4E (0.32) | XDHSLC22A12KDM4EMAPTHSD17B10 | |
| SCHEMBL23617296 | 0.68 | HSP90AB1 (0.46) | KDM4EMAPTHSD17B10POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3687506-B1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARM INC (US) | 2021-07-07 | — | — | EP | disclosed |