Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1792326 | 0.79 | TSHR (0.55) | LMNASMN1; SMN2TSHRCYP1A2CYP3A4 | |
| SCHEMBL3726705 | 0.79 | LMNA (0.50) | LMNASMN1; SMN2TSHRCYP1A2CYP3A4 | |
| SCHEMBL23617044 | 0.79 | APLNR (0.50) | TSHRKMT2ATAAR1MAPTMEN1 | |
| SCHEMBL23616906 | 0.79 | AKR1B1 (0.47) | TSHRCYP2D6KMT2AIDO1TAAR1 | |
| SCHEMBL17938175 | 0.78 | LMNA (0.56) | LMNASMN1; SMN2TSHRKMT2AIDO1 | |
| Hydrochloric Acid SCHEMBL6406497 | 0.78 | LMNA (0.49) | LMNASMN1; SMN2TSHRCYP1A2CYP3A4 | |
| SCHEMBL28899623 | 0.77 | IDO1 (0.40) | LMNATSHRCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8783162 | 0.77 | TSHR (0.36) | SMN1; SMN2TSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7634089 | 0.77 | KMT2A (0.54) | LMNASMN1; SMN2TSHRCYP1A2CYP3A4 | |
| SCHEMBL28463483 | 0.75 | SLC6A2 (0.41) | LMNATSHRCYP1A2CYP3A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3687506-B1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARM INC (US) | 2021-07-07 | — | — | EP | disclosed |