Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23617021 | 0.81 | APLNR (0.50) | APLNRALDH1A1POLBTDP1MEN1 | |
| SCHEMBL21455751 | 0.81 | ALDH1A1 (0.53) | APLNRALDH1A1POLBTDP1MEN1 | |
| SCHEMBL30482840 | 0.81 | ALDH1A1 (0.53) | APLNRALDH1A1POLBTDP1MEN1 | |
| SCHEMBL23617043 | 0.80 | APLNR (0.56) | APLNRALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL23616865 | 0.79 | LMNA (0.50) | MEN1KMT2ATSHRTAAR1MAPT | |
| SCHEMBL10650486 | 0.77 | MAPT (0.53) | ALDH1A1MEN1KMT2AMAPK1MAPT | |
| SCHEMBL8452208 | 0.77 | MEN1 (0.49) | APLNRALDH1A1POLBTDP1MEN1 | |
| SCHEMBL3027059 | 0.76 | APLNR (0.59) | APLNRALDH1A1MEN1KMT2ACA2 | |
| SCHEMBL6624872 | 0.75 | HSD17B10 (0.54) | APLNRALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL6622974 | 0.75 | HSD17B10 (0.54) | APLNRALDH1A1POLBTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3687506-B1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARM INC (US) | 2021-07-07 | — | — | EP | disclosed |