Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 6/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.38 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20531615 | 0.87 | CHRM5 (0.42) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL28286379 | 0.79 | ACHE (0.37) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL27733421 | 0.79 | CHRM5 (0.37) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL3840265 | 0.79 | LMNA (0.39) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL18686708 | 0.79 | — | — | |
| SCHEMBL28601326 | 0.77 | CHRM5 (0.39) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL28181175 | 0.76 | ACHE (0.42) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL13513183 | 0.76 | CHRNB2 (0.37) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL28497595 | 0.75 | CHRM5 (0.41) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL18686718 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3845061-A1 | HAPLOID INDUCTION COMPOSITIONS AND METHODS FOR USE THEREFOR | Syngenta Participations AG (CH) | 2021-07-07 | — | — | EP | disclosed |