Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2361158 | 0.93 | TSHR (0.37) | TSHRALDH1A1 | |
| SCHEMBL9312908 | 0.91 | TSHR (0.41) | TSHR | |
| SCHEMBL3761507 | 0.91 | TSHR (0.41) | TSHR | |
| SCHEMBL6781444 | 0.89 | TSHR (0.32) | TSHRALDH1A1 | |
| SCHEMBL6785024 | 0.89 | TSHR (0.32) | TSHRALDH1A1 | |
| SCHEMBL2968538 | 0.84 | TSHR (0.30) | TSHRALDH1A1 | |
| SCHEMBL6783239 | 0.82 | TSHR (0.33) | TSHR | |
| SCHEMBL6787500 | 0.82 | TSHR (0.33) | TSHR | |
| SCHEMBL7764316 | 0.78 | TSHR (0.35) | TSHRALDH1A1 | |
| SCHEMBL2361867 | 0.78 | TSHR (0.35) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231740-B1 | MOISTURE-CURABLE SILYLATED POLYUREA AND ADHESIVE, SEALANT AND COATING COMPOSITIONS CONTAINING SAME | MOMENTIVE PERFORMANCE MAT INC (US) | 2011-08-24 | — | — | EP | claimed |
| US-20090041673-A1 | Thermally Crosslinked Contrast Agents | ANYGEN CO., LTD. (KR) | 2009-02-12 | — | — | US | disclosed |
| US-20040259992-A1 | Two-component adhesion promoter combination of an unsaturated alkoxysilane and a mercaptoalkyl alkoxysilane, for use in dental prostheses | 3M ESPE AG (DE) | 2004-12-23 | — | — | US | disclosed |
| EP-0705838-B1 | Process for the preparation of silane polysulfides | CROMPTON CORP (US) | 2001-05-23 | — | — | EP | disclosed |
| US-5596116-A | Process for the preparation of silane polysulfides | OSI SPECIALTIES, INC. (US) | 1997-01-21 | — | — | US | disclosed |
| EP-0705838-A2 | Process for the preparation of silane polysulfides | OSi SPECIALTIES, INC. (US) | 1996-04-10 | — | — | EP | disclosed |
| US-5489701-A | REACTING SULFUR AND A HALOHYDROCARBYLALKOXYSILANE WITH THE REACTION PRODUCT OF HYDROGEN SULFIDE GAS AND A METAL ALKOXIDE SOLUTION | OSI SPECIALTIES, INC. (US) | 1996-02-06 | — | — | US | disclosed |
| US-5466848-A | Sulfiding sodium ethoxide with hydrogen sulfide to make sodium sulfide; reacting with sulfur to tetrasulfide; reacting with halohydrocarbylalkoxysilane | OSI SPECIALTIES, INC. (US) | 1995-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259992-A1 | Two-component adhesion promoter combination of an unsaturated alkoxysilane and a mercaptoalkyl alkoxysilane, for use in dental prostheses | ITGA2, ITGB2, ITGA2B | TSHR 3882/4885ALDH1A1 453/4885 |
| US-20090041673-A1 | Thermally Crosslinked Contrast Agents | HSP90AA1, TBCA, HSPA1A | TSHR 1969/4885ALDH1A1 1990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.