SCHEMBL23618593

SCHEMBL23618593

Ic1c2ccccc2nc2ncccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
CYP3A4 P08684 1/20 0.41
DHODH Q02127 1/20 0.41
ABCG2 Q9UNQ0 2/20 0.41
KDM4E B2RXH2 2/20 0.40
MAPT P10636 1/20 0.40
MAOA P21397 2/20 0.38
ACHE P22303 2/20 0.38
GLA P06280 1/20 0.38
CHRM2 P08172 1/20 0.38
ADRA2A P08913 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
CHRM1 P11229 1/20 0.38
HPGD P15428 1/20 0.38
NQO2 P16083 1/20 0.38
DRD1 P21728 1/20 0.38
SLC6A2 P23975 1/20 0.38
CASP1 P29466 1/20 0.38
ADRA1A P35348 1/20 0.38
OPRM1 P35372 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13445183 0.79 KDM4E (0.56) ALDH1A1KDM4EMAPTMAOAACHE
SCHEMBL28616122 0.77 ACHE (0.63) ALDH1A1CYP3A4KDM4EMAPTMAOA
SCHEMBL27110193 0.76 KDM4E (0.38) ALDH1A1CYP3A4DHODHABCG2KDM4E
SCHEMBL8967704 0.73 CYP3A4 (0.46) ALDH1A1CYP3A4DHODHKDM4EMAPT
SCHEMBL15346406 0.73 HCAR2 (0.46) ALDH1A1CYP3A4DHODHABCG2KDM4E
SCHEMBL24604916 0.73 DHODH (0.41) ALDH1A1CYP3A4DHODHABCG2KDM4E
SCHEMBL1650848 0.72 PLAUR (0.47) ALDH1A1CYP3A4DHODHKDM4EMAPT
Hydrochloric Acid SCHEMBL5336924 0.70 PLAUR (0.46) ALDH1A1CYP3A4DHODHKDM4EGLA
Phenazine SCHEMBL19970688 0.70 MAPT (0.55) ALDH1A1CYP3A4KDM4EMAPTACHE
SCHEMBL28915934 0.70 MAPT (0.55) ALDH1A1CYP3A4KDM4EMAPTACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021135182-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS 陕西莱特光电材料股份有限公司 2021-07-08 WO disclosed