SCHEMBL13445183

SCHEMBL13445183

Ic1c2ccccc2nc2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.56
ALDH1A1 P00352 7/20 0.56
GLA P06280 6/20 0.56
HPGD P15428 5/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
MAOA P21397 2/20 0.56
CASP1 P29466 2/20 0.56
CASP7 P55210 2/20 0.56
HSD17B10 Q99714 2/20 0.56
ACHE P22303 2/20 0.56
CHRM2 P08172 1/20 0.56
ADRA2A P08913 1/20 0.56
ADORA3 P0DMS8 1/20 0.56
CHRM1 P11229 1/20 0.56
NQO2 P16083 1/20 0.56
DRD1 P21728 1/20 0.56
SLC6A2 P23975 1/20 0.56
ADRA1A P35348 1/20 0.56
OPRM1 P35372 1/20 0.56
KCNH2 Q12809 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL44256 0.79 KDM4E (0.41) KDM4EALDH1A1GLAHPGDSMN1; SMN2
SCHEMBL9980118 0.79 ALDH1A1 (0.52) KDM4EALDH1A1GLAHPGDSMN1; SMN2
SCHEMBL23618593 0.79 ALDH1A1 (0.43) KDM4EALDH1A1GLAHPGDSMN1; SMN2
SCHEMBL20080995 0.79 MAOA (0.50) KDM4EALDH1A1GLAHPGDSMN1; SMN2
SCHEMBL18799902 0.77 GPR3 (0.47) KDM4EALDH1A1GLAHPGDSMN1; SMN2
SCHEMBL11985944 0.77 GPR3 (0.57) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL1502392 0.77 ALDH1A1 (0.62) KDM4EALDH1A1GLAHPGDSMN1; SMN2
Aminacrine SCHEMBL30355377 0.76 HSD17B10 (0.95) KDM4EALDH1A1GLAHPGDSMN1; SMN2
SCHEMBL1133452 0.75 ALDH1A1 (0.41) KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10
SCHEMBL29549717 0.75 ALDH1A1 (0.41) KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3208271-B1 NITROGEN-CONTAINING POLYCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING SAME LG CHEMICAL LTD (KR) 2021-07-21 EP disclosed
WO-2021135182-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS 陕西莱特光电材料股份有限公司 2021-07-08 WO disclosed
WO-2020243037-A1 BISAMINOQUINOLINES AND BISAMINOACRIDINES COMPOUNDS AND METHODS OF THEIR USE THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2020-12-03 WO disclosed
EP-3208271-A2 NITROGEN-CONTAINING POLYCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING SAME LG Chem, Ltd. (KR) 2017-08-23 EP disclosed
EP-2161319-A2 Benzo(c)phenanthrene derivatives and organic electroluminescent device using the same Gracel Display Inc. (KR) 2010-03-10 EP disclosed