Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MLLT1 | Q03111 | 2/20 | 0.34 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23618933 | 0.72 | L3MBTL1 (0.38) | KDM4ENPC1L3MBTL1 | |
| SCHEMBL23619049 | 0.71 | LRRK2 (0.39) | KDM4ENPC1L3MBTL1 | |
| SCHEMBL5250334 | 0.71 | DNMT1 (0.46) | KDM4EMLLT1DNMT1SCN5AMAOB | |
| SCHEMBL23618941 | 0.69 | IDO1 (0.41) | KDM4ENPC1L3MBTL1 | |
| SCHEMBL23618929 | 0.66 | KDM4E (0.37) | KDM4ENPC1L3MBTL1 | |
| SCHEMBL23618942 | 0.66 | KDM4E (0.40) | KDM4ENPC1L3MBTL1 | |
| SCHEMBL10069688 | 0.62 | SMN1; SMN2 (0.54) | KDM4ENPC1L3MBTL1 | |
| SCHEMBL23619041 | 0.62 | RAB9A (0.67) | KDM4ENPC1L3MBTL1 | |
| SCHEMBL18911786 | 0.62 | HCAR3 (0.54) | KDM4ENPC1 | |
| SCHEMBL1599397 | 0.60 | SMN1; SMN2 (0.38) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021136431-A1 | BENZO[D][1,2,3]TRIAZOLE ETHER COMPOUND | 南京明德新药研发有限公司 | 2021-07-08 | — | — | WO | disclosed |