Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 4/20 | 0.38 |
| ▸ | RORC | P51449 | 4/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23619013 | 0.91 | PDE2A (0.40) | PDE2ARORCUTS2RKCNK3PIK3CD | |
| SCHEMBL23619095 | 0.88 | RORC (0.43) | PDE2ARORCUTS2RHDAC1 | |
| SCHEMBL23619026 | 0.87 | RORC (0.49) | RORC | |
| SCHEMBL23619091 | 0.83 | RORC (0.43) | PDE2ARORCUTS2RHDAC1 | |
| SCHEMBL23619004 | 0.81 | RORC (0.49) | RORCSCN9A | |
| SCHEMBL23619010 | 0.79 | PDE2A (0.39) | PDE2ARORCUTS2RHDAC1 | |
| SCHEMBL28618414 | 0.79 | RORC (0.42) | PDE2ARORCPIK3CDSCN9A | |
| SCHEMBL23619014 | 0.79 | RORC (0.42) | PDE2ARORCPIK3CDSCN9A | |
| SCHEMBL23619005 | 0.77 | ROCK2 (0.45) | SCN9AHDAC1 | |
| SCHEMBL23619017 | 0.75 | RORC (0.48) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021136339-A1 | AMIDE COMPOUND WITH BICYCLIC STRUCTURE AND USE THEREOF IN DRUG | 广东东阳光药业有限公司 | 2021-07-08 | — | — | WO | disclosed |