Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 6/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | WDR91 | A4D1P6 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23619095 | 0.94 | RORC (0.43) | RORCPTGER4HDAC1HDAC6UTS2R | |
| SCHEMBL23619021 | 0.88 | RORC (0.48) | RORC | |
| SCHEMBL28629232 | 0.88 | RORC (0.48) | RORC | |
| SCHEMBL23619010 | 0.86 | PDE2A (0.39) | RORCPTGER4HDAC1HDAC6UTS2R | |
| SCHEMBL23619113 | 0.86 | ROCK2 (0.45) | RORCHDAC1HDAC6 | |
| SCHEMBL23619031 | 0.83 | PDE2A (0.38) | RORCHDAC1UTS2RPDE2A | |
| SCHEMBL23619017 | 0.81 | RORC (0.48) | RORC | |
| SCHEMBL28921695 | 0.81 | RORC (0.48) | RORC | |
| SCHEMBL23619089 | 0.80 | RORC (0.42) | RORCPTGER4PDE2A | |
| SCHEMBL28615097 | 0.80 | RORC (0.42) | RORCPTGER4PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021136339-A1 | AMIDE COMPOUND WITH BICYCLIC STRUCTURE AND USE THEREOF IN DRUG | 广东东阳光药业有限公司 | 2021-07-08 | — | — | WO | disclosed |