Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2810664 | 0.84 | MAPK1 (0.54) | ESR2UCHL1MAPK1NR1H2SCN9A | |
| SCHEMBL29587134 | 0.84 | MAPK1 (0.54) | ESR2UCHL1MAPK1NR1H2SCN9A | |
| SCHEMBL17687111 | 0.80 | ADORA1 (0.44) | ESR2UCHL1MAPK1NR1H2SCN9A | |
| SCHEMBL5776971 | 0.78 | ESR2 (0.50) | ESR2UCHL1MAPK1NR1H2SCN9A | |
| SCHEMBL29865391 | 0.78 | ESR2 (0.46) | ESR2UCHL1MAPK1NR1H2SCN9A | |
| SCHEMBL31560132 | 0.77 | TRPV1 (0.39) | ESR2UCHL1MAPK1NR1H2SCN9A | |
| SCHEMBL30418077 | 0.76 | UCHL1 (0.48) | ESR2UCHL1MAPK1NR1H2SCN9A | |
| SCHEMBL10289745 | 0.76 | ESR2 (0.53) | ESR2UCHL1MAPK1NR1H2SCN9A | |
| SCHEMBL23611290 | 0.76 | GHSR (0.38) | UCHL1 | |
| SCHEMBL11997414 | 0.76 | ESR2 (0.55) | ESR2UCHL1MAPK1NR1H2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115066417-B | Factor XIa inhibitors | 上海京新生物医药有限公司 | 2025-05-02 | — | — | CN | disclosed |
| CN-115066417-A | Factor XIa inhibitors | 上海京新生物医药有限公司 | 2022-09-16 | — | — | CN | disclosed |
| WO-2021136390-A1 | BLOOD COAGULATION FACTOR XIA INHIBITOR | 上海京新生物医药有限公司 | 2021-07-08 | — | — | WO | disclosed |