Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | JAK1 | P23458 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12141197 | 0.91 | NAMPT (0.43) | MAPTPOLBHTTKEAP1ALDH1A1 | |
| SCHEMBL24638071 | 0.83 | MAPT (0.38) | MAPTPOLBHTTHPGDHSD11B1 | |
| SCHEMBL12142171 | 0.81 | BLM (0.40) | MAPTALDH1A1NAMPTTSHRCHRNB2 | |
| SCHEMBL21840081 | 0.80 | ALDH1A1 (0.36) | MAPTHTTHPGDALDH1A1USP2 | |
| SCHEMBL13900834 | 0.80 | QDPR (0.45) | MAPTHTTALDH1A1NAMPTKDM4E | |
| SCHEMBL17342884 | 0.78 | KEAP1 (0.43) | MAPTPOLBHTTHPGDJAK1 | |
| SCHEMBL19454525 | 0.75 | MAPT (0.38) | MAPTALDH1A1GAAALOX15TSHR | |
| SCHEMBL20458849 | 0.75 | NAMPT (0.41) | MAPTNAMPTTSHR | |
| SCHEMBL8117386 | 0.75 | MAPT (0.43) | MAPTPOLBHTTALDH1A1KDM4E | |
| SCHEMBL25628761 | 0.75 | MEN1 (0.37) | MAPTHPGDALDH1A1NAMPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021136238-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF | 武汉朗来科技发展有限公司 | 2021-07-08 | — | — | WO | disclosed |