SCHEMBL23619683

SCHEMBL23619683

CC(C)c1c(N)cncc1C(F)(F)F

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16857176 0.80 CFTR (0.32)
SCHEMBL24850143 0.78 TRPA1 (0.33)
SCHEMBL23620109 0.78 CYP11B1 (0.31)
SCHEMBL24039953 0.78 CYP11B2 (0.34)
SCHEMBL21937886 0.77 CYP11B2 (0.34)
SCHEMBL24713322 0.74 CYP11B2 (0.33)
SCHEMBL9953896 0.72 MAP3K12 (0.37) HPGDHSD17B10
SCHEMBL24039917 0.72 CYP17A1 (0.36)
SCHEMBL23278084 0.71 UHRF1 (0.32)
SCHEMBL25413584 0.71 P2RX7 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021136238-A1 FUSED RING COMPOUND AND APPLICATION THEREOF 武汉朗来科技发展有限公司 2021-07-08 WO disclosed