Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | BUB1 | O43683 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14112126 | 0.77 | USP2 (0.40) | USP2SMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL29092562 | 0.76 | BUB1 (0.41) | SCN5ASCN9AKDM4EKDM1ABUB1 | |
| SCHEMBL23610164 | 0.74 | LMNA (0.30) | THRB | |
| SCHEMBL13588590 | 0.74 | GPR119 (0.38) | USP2SMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL12411168 | 0.74 | PDE4B (0.39) | USP2SMN1; SMN2THRBKDM1APDE4A | |
| SCHEMBL2070705 | 0.73 | HDAC1 (0.38) | USP2SMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL2738361 | 0.72 | LMNA (0.44) | USP2SMN1; SMN2MAPTTHRBKDM1A | |
| SCHEMBL3432319 | 0.71 | USP2 (0.41) | USP2SMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL102885 | 0.71 | SMN1; SMN2 (0.42) | SCN5ASCN9AUSP2SMN1; SMN2KDM4E | |
| SCHEMBL21915012 | 0.71 | KDM1A (0.37) | USP2SMN1; SMN2THRBKDM1APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210206725-A1 | PIPERLONGUMINE ANALOGUES AND USES THEREOF | BIOVENTURES, LLC | 2021-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210206725-A1 | PIPERLONGUMINE ANALOGUES AND USES THEREOF | AGER, MCL1, TP53 | SCN5A 4798/4885SCN9A 4669/4885USP2 425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.