Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | ITK | Q08881 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10238325 | 0.86 | KDM4E (0.52) | KDM4ELMNANPC1RAB9AMAPT | |
| SCHEMBL3370266 | 0.85 | HCAR3 (0.50) | KDM4ENPC1RAB9AFGFR1PTGER4 | |
| SCHEMBL2362614 | 0.84 | KDM4E (0.56) | KDM4EEHMT2PTGER4ACSS2CNR2 | |
| SCHEMBL19029395 | 0.82 | KDM4E (0.56) | KDM4ELMNANPC1RAB9AMAPT | |
| SCHEMBL31489 | 0.80 | RAB9A (0.72) | KDM4ELMNANPC1RAB9AMAPT | |
| SCHEMBL29989068 | 0.80 | RAB9A (0.72) | KDM4ELMNANPC1RAB9AMAPT | |
| SCHEMBL9412502 | 0.80 | KMT2A (0.44) | LMNANPC1RAB9AMAPTPTGER4 | |
| SCHEMBL28439988 | 0.79 | KDM4E (0.56) | KDM4ELMNANPC1RAB9AMAPT | |
| SCHEMBL30897550 | 0.79 | KDM4E (0.56) | KDM4ELMNANPC1RAB9AMAPT | |
| SCHEMBL4259457 | 0.79 | KDM4E (0.56) | KDM4ELMNANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011099832-A2 | NOVEL BENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CRYSTALGENOMICS, INC. (KR) | 2011-08-18 | — | — | WO | disclosed |