Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ACSS2 | Q9NR19 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2362098 | 0.80 | KDM4E (0.55) | ACSS2MAPTRAB9ANPC1LMNA | |
| SCHEMBL9249604 | 0.79 | HDAC1 (0.50) | KMT2AMAPTSMN1; SMN2TDP1RIPK2 | |
| SCHEMBL9412442 | 0.76 | MAPT (0.49) | KMT2AMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8863519 | 0.76 | HDAC1 (0.52) | KMT2AMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9251340 | 0.76 | HDAC1 (0.49) | RIPK2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL3370266 | 0.76 | HCAR3 (0.50) | ACSS2SMN1; SMN2RAB9ANPC1HPGD | |
| Hydrochloric Acid SCHEMBL9255053 | 0.76 | HDAC1 (0.51) | KMT2AMAPTSMN1; SMN2RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL9252320 | 0.76 | HDAC1 (0.51) | KMT2AMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9248580 | 0.76 | HDAC1 (0.51) | KMT2AMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9255968 | 0.76 | HDAC1 (0.51) | MAPTSMN1; SMN2RIPK2HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611660-A2 | Condensed 5-membered heterocycles, process for their preparation and medicines containing these compounds | Dr. Karl Thomae GmbH (DE) | 1994-08-24 | — | — | EP | disclosed |