Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24241002 | 0.78 | MEN1 (0.37) | LMNAPARP1ALDH1A1PKMMEN1 | |
| SCHEMBL17307154 | 0.76 | DPP4 (0.40) | LMNAPARP1ALDH1A1PKMPDE2A | |
| SCHEMBL6364767 | 0.76 | LMNA (0.38) | LMNAPARP1ALDH1A1PKMPDE2A | |
| SCHEMBL18405893 | 0.76 | LMNA (0.38) | LMNAPARP1ALDH1A1PKMPDE2A | |
| SCHEMBL24854117 | 0.75 | LMNA (0.37) | LMNAPARP1ALDH1A1PKMPDE2A | |
| SCHEMBL22380086 | 0.71 | ALDH1A1 (0.40) | LMNAPARP1ALDH1A1PKMPDE2A | |
| SCHEMBL2339392 | 0.71 | LMNA (0.32) | LMNAPARP1MEN1KMT2ACCR1 | |
| SCHEMBL534330 | 0.70 | PARP1 (0.50) | LMNAPARP1ALDH1A1MEN1KMT2A | |
| SCHEMBL6397525 | 0.67 | LMNA (0.42) | LMNAPARP1ALDH1A1PKMMEN1 | |
| SCHEMBL4246899 | 0.65 | PDPK1 (0.39) | LMNAPARP1ALDH1A1PKMPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011099832-A2 | NOVEL BENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CRYSTALGENOMICS, INC. (KR) | 2011-08-18 | — | — | WO | disclosed |