Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28109769 | 0.81 | KDM4E (0.38) | GPR3MAPTALDH1A1KMT2ATP53 | |
| SCHEMBL27340956 | 0.80 | PGR (0.38) | GPR3MAPTALDH1A1PDK2LMNA | |
| SCHEMBL5520562 | 0.79 | MAPT (0.47) | GPR3MAPTALDH1A1PDK2NSD2 | |
| SCHEMBL6676651 | 0.79 | GPR3 (0.62) | GPR3MAPTALDH1A1PDK2NSD2 | |
| SCHEMBL11783880 | 0.77 | HTR2B (0.51) | GPR3MAPTALDH1A1PDK2KMT2A | |
| SCHEMBL28058725 | 0.77 | BCHE (0.39) | GPR3MAPTALDH1A1PDK2LMNA | |
| Water SCHEMBL27413384 | 0.76 | HTR2B (0.50) | GPR3MAPTALDH1A1PDK2KMT2A | |
| SCHEMBL27342829 | 0.73 | GPR3 (0.38) | GPR3KMT2APGRHTR2BHTR7 | |
| SCHEMBL1261847 | 0.73 | MEN1 (0.45) | GPR3MAPTALDH1A1EGFRLMNA | |
| SCHEMBL3857913 | 0.72 | PTGS2 (0.43) | GPR3MAPTALDH1A1NSD2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377909-B | Ultra high molecular weight polyethylene particles and the formed body formed by it | 东曹株式会社 | 2018-04-03 | — | — | CN | disclosed |
| CN-103946245-B | Catalyst for olefin polymerization and copolymerization and method for olefin polymerization or copolymerization using the same | 韩华道达尔有限公司 | 2018-02-27 | — | — | CN | disclosed |
| EP-1553985-B1 | BIPHENYLS AS IMAGING AGENTS IN ALZHEIMER'S DISEASE | UNIV PENNSYLVANIA (US) | 2011-08-31 | — | — | EP | disclosed |
| US-20070254889-A1 | Compounds and methods useful for rescuing cells from beta-amyloid toxicity and treatment of Alzheimer's disease | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2007-11-01 | — | — | US | disclosed |
| US-20050271584-A1 | Biphenyls and fluorenes as imaging agents in alzheimer's disease | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2005-12-08 | — | — | US | disclosed |
| EP-1553985-A2 | BIPHENYLS AND FLUORENES AS IMAGING AGENTS IN ALZHEIMER'S DISEASE | The Trustees of The University of Pennsylvania (US) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004032975-A2 | BIPHENYLS AND FLUORENES AS IMAGING AGENTS IN ALZHEIMER'S DISEASE | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2004-04-22 | — | — | WO | disclosed |
| CN-1059712-A | Oxime carbonates as mycocide | DU PONT (US) | 1992-03-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254889-A1 | Compounds and methods useful for rescuing cells from beta-amyloid toxicity and treatment of Alzheimer's disease | APP, BACE1, IAPP | GPR3 3746/4885MAPT 13/4885ALDH1A1 1209/4885 |
| US-20050271584-A1 | Biphenyls and fluorenes as imaging agents in alzheimer's disease | APP, BACE2, BACE1 | GPR3 1065/4885MAPT 4/4885ALDH1A1 1533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.