Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10238327 | 0.89 | MEN1 (0.47) | CNR2CNR1MEN1KMT2AGRM2 | |
| SCHEMBL1748120 | 0.81 | SMN1; SMN2 (0.53) | CNR2CNR1MEN1KMT2AGRM2 | |
| SCHEMBL13057628 | 0.79 | ACSS2 (0.43) | CNR2MEN1KMT2AGRM2PKM | |
| SCHEMBL8058929 | 0.79 | KDM4E (0.50) | MEN1KMT2AGRM2PKMHTR3E | |
| SCHEMBL2711203 | 0.78 | PKM (0.49) | CNR2CNR1MEN1KMT2AGRM2 | |
| SCHEMBL7770175 | 0.78 | MEN1 (0.46) | CNR2CNR1MEN1KMT2AGRM2 | |
| SCHEMBL2360807 | 0.78 | CACNA1D (0.52) | CNR2CNR1MEN1KMT2AGRM2 | |
| SCHEMBL19664446 | 0.77 | GRM2 (0.53) | CNR2CNR1MEN1KMT2AGRM2 | |
| SCHEMBL20495470 | 0.76 | FAAH (0.39) | MEN1KMT2AACSS2 | |
| SCHEMBL10251494 | 0.75 | MEN1 (0.43) | CNR2CNR1MEN1KMT2AGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011099832-A2 | NOVEL BENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CRYSTALGENOMICS, INC. (KR) | 2011-08-18 | — | — | WO | disclosed |