Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 6/20 | 0.62 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.62 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 8/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.61 |
| ▸ | MEN1 | O00255 | 7/20 | 0.61 |
| ▸ | ATM | Q13315 | 3/20 | 0.61 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.61 |
| ▸ | HTR1A | P08908 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | APAF1 | O14727 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RGS12 | O14924 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19872904 | 0.92 | USP2 (0.68) | KEAP1NFE2L2TLR9USP2KMT2A | |
| SCHEMBL22099930 | 0.89 | KEAP1 (0.60) | KEAP1NFE2L2TLR9USP2KMT2A | |
| SCHEMBL12660523 | 0.87 | KEAP1 (0.61) | KEAP1NFE2L2TLR9USP2KMT2A | |
| SCHEMBL16085240 | 0.86 | KEAP1 (0.60) | KEAP1NFE2L2TLR9USP2KMT2A | |
| SCHEMBL14329995 | 0.86 | KEAP1 (0.57) | KEAP1NFE2L2TLR9USP2KMT2A | |
| SCHEMBL23624808 | 0.85 | KMT2A (0.54) | KEAP1NFE2L2TLR9USP2KMT2A | |
| SCHEMBL20385847 | 0.85 | KEAP1 (0.61) | KEAP1NFE2L2TLR9USP2KMT2A | |
| SCHEMBL22361783 | 0.81 | HEXA (0.56) | CYP1B1HTR1AMAPTKDM4EALDH1A1 | |
| SCHEMBL23625037 | 0.81 | MEN1 (0.62) | TLR9KMT2AMEN1MAPTKDM4E | |
| SCHEMBL9437193 | 0.80 | KMT2A (0.78) | KEAP1NFE2L2TLR9USP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210205461-A1 | Rapidly Released Bioorthogonal Caging Groups | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2021-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210205461-A1 | Rapidly Released Bioorthogonal Caging Groups | CBR3, CBR1, CNOT9 | KEAP1 1501/4885NFE2L2 3278/4885TLR9 168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.