Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.54 |
| ▸ | MEN1 | O00255 | 10/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | USP2 | O75604 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | RGS12 | O14924 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 5/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | ATM | Q13315 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23624902 | 0.85 | KEAP1 (0.62) | KMT2AMEN1MAPTUSP2LMNA | |
| SCHEMBL22361783 | 0.81 | HEXA (0.56) | MAPTALDH1A1POLBCYP1B1RAB9A | |
| SCHEMBL23625037 | 0.81 | MEN1 (0.62) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL12243699 | 0.80 | TERT (0.55) | KMT2AMEN1LMNARGS12HTT | |
| SCHEMBL12640365 | 0.80 | TERT (0.55) | KMT2AMEN1LMNARGS12HTT | |
| SCHEMBL25396585 | 0.79 | RAB9A (0.58) | KMT2AMAPTALDH1A1POLBL3MBTL1 | |
| SCHEMBL29451539 | 0.79 | RAB9A (0.58) | KMT2AMAPTALDH1A1POLBL3MBTL1 | |
| SCHEMBL20400184 | 0.79 | RAB9A (0.58) | KMT2AMAPTALDH1A1POLBL3MBTL1 | |
| SCHEMBL3091241 | 0.79 | RAB9A (0.58) | KMT2AMAPTALDH1A1POLBL3MBTL1 | |
| SCHEMBL30536704 | 0.79 | RAB9A (0.58) | KMT2AMAPTALDH1A1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210205461-A1 | Rapidly Released Bioorthogonal Caging Groups | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2021-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210205461-A1 | Rapidly Released Bioorthogonal Caging Groups | CBR3, CBR1, CNOT9 | KMT2A 4165/4885MEN1 2528/4885MAPT 4028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.