Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 5/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | PLEC | Q15149 | 1/20 | 0.51 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.47 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 6/20 | 0.44 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12637546 | 0.86 | USP2 (0.57) | USP2L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL12637647 | 0.86 | USP2 (0.72) | USP2L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL10060277 | 0.85 | POLB (0.59) | USP2L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL18932154 | 0.85 | USP2 (0.56) | USP2L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL16231516 | 0.85 | USP2 (0.64) | USP2L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL17549805 | 0.85 | USP2 (0.51) | USP2L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL107875 | 0.84 | USP2 (0.76) | USP2L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL29781098 | 0.84 | USP2 (0.76) | USP2L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL29591827 | 0.84 | USP2 (0.76) | USP2L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL8947940 | 0.84 | USP2 (0.58) | USP2L3MBTL1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210206791-A1 | SELECTIVE METAL-MEDIATED ARYLATION OF DICHALCOGENIDES IN BIOMOLECULES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2021-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210206791-A1 | SELECTIVE METAL-MEDIATED ARYLATION OF DICHALCOGENIDES IN BIOMOLECULES | SCLY, SELENOI, PTMS | USP2 972/4885L3MBTL1 2229/4885POLB 3413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.