SCHEMBL23625545

SCHEMBL23625545

Cc1ccc(-c2ccc(-c3ccc(C#N)c4ccccc34)cc2C#N)cc1C

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
AR P10275 4/20 0.43
ALDH1A1 P00352 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
IMPDH2 P12268 1/20 0.41
IMPDH1 P20839 1/20 0.41
NSD2 O96028 3/20 0.40
XDH P47989 2/20 0.39
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
TSHR P16473 1/20 0.38
PGR P06401 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23624587 0.92 AR (0.48) ARALDH1A1NPSR1IMPDH2IMPDH1
SCHEMBL24617028 0.85 AR (0.45) ARIMPDH2IMPDH1NSD2XDH
SCHEMBL23625513 0.79 AR (0.39) ARALDH1A1NPSR1CYP11B1CYP11B2
SCHEMBL6152302 0.77 IMPDH2 (0.49) ARALDH1A1NPSR1IMPDH2IMPDH1
SCHEMBL24617488 0.76 AR (0.43) ARIMPDH2IMPDH1CYP11B1CYP11B2
SCHEMBL23624462 0.76 IMPDH2 (0.47) ARALDH1A1NPSR1IMPDH2IMPDH1
SCHEMBL854444 0.74 CYP1A2 (0.59) ARALDH1A1IMPDH2IMPDH1NSD2
SCHEMBL15856557 0.74 MCL1 (0.52) ARXDHCYP11B1CYP11B2TSHR
SCHEMBL23625535 0.74 AR (0.45) ARALDH1A1NPSR1IMPDH2IMPDH1
SCHEMBL21188814 0.74 TSHR (0.55) ARALDH1A1CYP11B1CYP11B2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021135516-A1 ORGANIC COMPOUND, ELECTRONIC COMPONENT AND ELECTRONIC APPARATUS 陕西莱特光电材料股份有限公司 2021-07-08 WO disclosed