SCHEMBL23624587

SCHEMBL23624587

Cc1ccc(-c2ccc(-c3ccc(C#N)c4ccccc34)cc2C)cc1C

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AR P10275 4/20 0.48
ALDH1A1 P00352 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
IMPDH2 P12268 1/20 0.42
IMPDH1 P20839 1/20 0.42
NSD2 O96028 5/20 0.41
TSHR P16473 1/20 0.39
CYP11B1 P15538 2/20 0.39
CYP11B2 P19099 2/20 0.39
PGR P06401 1/20 0.38
CYP1A2 P05177 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
KDM4E B2RXH2 1/20 0.37
GALR3 O60755 1/20 0.37
GAA P10253 1/20 0.37
HPGD P15428 1/20 0.37
TGFBR1 P36897 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23625545 0.92 AR (0.43) ARALDH1A1NPSR1IMPDH2IMPDH1
SCHEMBL6152302 0.78 IMPDH2 (0.49) ARALDH1A1NPSR1IMPDH2IMPDH1
SCHEMBL24617028 0.77 AR (0.45) ARIMPDH2IMPDH1NSD2PGR
SCHEMBL23624462 0.77 IMPDH2 (0.47) ARALDH1A1NPSR1IMPDH2IMPDH1
SCHEMBL23625612 0.76 IMPDH2 (0.46) ARIMPDH2IMPDH1NSD2TSHR
SCHEMBL854444 0.75 CYP1A2 (0.59) ARALDH1A1IMPDH2IMPDH1NSD2
SCHEMBL15856557 0.75 MCL1 (0.52) ARTSHRCYP11B1CYP11B2PGR
SCHEMBL25767772 0.75 CYP11B1 (0.45) ALDH1A1CYP11B1CYP11B2
SCHEMBL23625535 0.75 AR (0.45) ARALDH1A1NPSR1IMPDH2IMPDH1
SCHEMBL26017273 0.74 ALDH1A1 (0.49) ARALDH1A1NPSR1TSHRCYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021135725-A1 ORGANIC COMPOUND, ELECTRONIC DEVICE AND ELECTRONIC APPARATUS USING SAME 陕西莱特光电材料股份有限公司 2021-07-08 WO disclosed