SCHEMBL23625615

SCHEMBL23625615

CC(C)c1ccc(C#N)c2cc(C#N)ccc12

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
IMPDH2 P12268 2/20 0.35
IMPDH1 P20839 2/20 0.35
PTGDR2 Q9Y5Y4 1/20 0.34
AR P10275 3/20 0.33
ALDH1A1 P00352 1/20 0.32
CYP2A6 P11509 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
DPP4 P27487 2/20 0.32
TRPV1 Q8NER1 1/20 0.32
ACE2 Q9BYF1 1/20 0.31
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
GUSB P08236 2/20 0.30
PDE5A O76074 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19425844 0.80 PTGDR2 (0.42) IMPDH2IMPDH1PTGDR2ARALDH1A1
SCHEMBL12263530 0.80 CYP2A6 (0.38) IMPDH2IMPDH1PTGDR2ARALDH1A1
SCHEMBL4734576 0.78 IMPDH2 (0.56) IMPDH2IMPDH1ARALDH1A1
SCHEMBL13377029 0.75 CYP2A6 (0.41) IMPDH2IMPDH1PTGDR2ALDH1A1CYP2A6
SCHEMBL19827022 0.75 AR (0.38) IMPDH2IMPDH1ARMAOAMAOB
SCHEMBL7725427 0.72 CA1 (0.49) ARALDH1A1TRPV1CA1CA2
SCHEMBL24617494 0.72 KIF11 (0.38) IMPDH2IMPDH1ARALDH1A1CYP2A6
SCHEMBL24617039 0.72 CA1 (0.49) IMPDH2IMPDH1CYP2A6TRPV1CA1
SCHEMBL16957761 0.72 PTGDR2 (0.34) IMPDH2IMPDH1PTGDR2ALDH1A1CYP2A6
SCHEMBL105403 0.72 ALDH1A1 (0.43) PTGDR2ARALDH1A1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021135516-A1 ORGANIC COMPOUND, ELECTRONIC COMPONENT AND ELECTRONIC APPARATUS 陕西莱特光电材料股份有限公司 2021-07-08 WO disclosed