Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19534376 | 0.86 | ADAMTS5 (0.47) | HPGDSNPC1RAB9AADAMTS5ADAMTS4 | |
| SCHEMBL19520703 | 0.86 | ADAMTS5 (0.47) | HPGDSNPC1RAB9AADAMTS5ADAMTS4 | |
| SCHEMBL19520702 | 0.86 | ADAMTS5 (0.47) | HPGDSNPC1RAB9AADAMTS5ADAMTS4 | |
| SCHEMBL21082225 | 0.86 | ALDH1A1 (0.47) | HPGDSNPC1RAB9AADAMTS5ADAMTS4 | |
| SCHEMBL19534377 | 0.86 | ALDH1A1 (0.47) | HPGDSNPC1RAB9AADAMTS5ADAMTS4 | |
| SCHEMBL16511799 | 0.83 | NPC1 (0.50) | NPC1RAB9ALMNARXFP1SMN1; SMN2 | |
| SCHEMBL21046252 | 0.82 | ADAMTS5 (0.43) | HPGDSNPC1RAB9AADAMTS5ADAMTS4 | |
| SCHEMBL19520694 | 0.82 | ADAMTS5 (0.43) | HPGDSNPC1RAB9AADAMTS5ADAMTS4 | |
| SCHEMBL19520692 | 0.82 | ADAMTS5 (0.43) | HPGDSNPC1RAB9AADAMTS5ADAMTS4 | |
| SCHEMBL21082092 | 0.78 | ANPEP (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210206715-A1 | Benzoylglycine Derivatives and Methods of Making and Using Same | DUKE UNIVERSITY (US) | 2021-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210206715-A1 | Benzoylglycine Derivatives and Methods of Making and Using Same | B3GAT3, GLO1, GLMN | HPGDS 918/4885NPC1 3680/4885RAB9A 1659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.