Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731375 | 0.82 | CCNE2 (0.40) | ABCG2ABCB1ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL15774297 | 0.81 | ALDH1A1 (0.42) | ABCG2ALDH1A1KDM4EL3MBTL1ROCK1 | |
| SCHEMBL30807952 | 0.78 | ALDH1A1 (0.40) | ABCG2ALDH1A1KDM4EL3MBTL1ROCK1 | |
| SCHEMBL29207395 | 0.78 | ALDH1A1 (0.40) | ABCG2ALDH1A1KDM4EL3MBTL1ROCK1 | |
| SCHEMBL522034 | 0.77 | CHRM3 (0.48) | ABCB1ALDH1A1KDM4EL3MBTL1ROCK1 | |
| SCHEMBL1561098 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KDM4EL3MBTL1ROCK1KMT2A | |
| SCHEMBL16266714 | 0.72 | KDM4E (0.47) | ABCG2ALDH1A1KDM4EROCK1KMT2A | |
| SCHEMBL27667052 | 0.72 | NAMPT (0.47) | ALDH1A1ROCK1KMT2ALMNACYP1A2 | |
| SCHEMBL13210725 | 0.71 | RAB9A (0.54) | ALDH1A1L3MBTL1KMT2ALMNAHTT | |
| SCHEMBL2354921 | 0.71 | ATM (0.61) | ABCG2ABCB1ALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011101229-A1 | DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-08-25 | — | — | WO | disclosed |