Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2362698 | 0.82 | ABCG2 (0.46) | KMT2AABCB1ABCG2L3MBTL1LMNA | |
| SCHEMBL4780539 | 0.79 | CHRM3 (0.45) | MEN1KMT2ACHRM3NPSR1CHRM2 | |
| SCHEMBL4602252 | 0.78 | CHRM3 (0.51) | MEN1KMT2ACHRM3NPSR1ROCK2 | |
| SCHEMBL5087704 | 0.77 | CHRM3 (0.47) | MEN1KMT2ACHRM3L3MBTL1LMNA | |
| SCHEMBL5081617 | 0.77 | CHRM3 (0.47) | MEN1KMT2ACHRM3L3MBTL1MAPT | |
| SCHEMBL5085060 | 0.75 | CHRM3 (0.49) | MEN1KMT2ACHRM3NPSR1ROCK2 | |
| SCHEMBL5084476 | 0.75 | ALDH1A1 (0.50) | CHRM3THRBNPSR1ROCK2ALDH1A1 | |
| SCHEMBL4602463 | 0.74 | NPC1 (0.47) | MEN1KMT2ACHRM3NPSR1ROCK2 | |
| SCHEMBL1128158 | 0.73 | NPC1 (0.45) | MEN1KMT2ACHRM3LMNANPSR1 | |
| SCHEMBL1128131 | 0.73 | CHRM3 (0.47) | KMT2ACHRM3THRBNPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008053044-A2 | HETARYL CARBON ACID-N-(BIPHEN-2-YL)AMIDE COMPOUNDS | BASF SE (DE) | 2008-05-08 | — | — | WO | disclosed |