Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15809607 | 0.78 | DNM1 (0.56) | DNM1KDM4ETSHRMEN1ALDH1A1 | |
| SCHEMBL24485546 | 0.77 | DNM1 (0.63) | DNM1KDM4ETSHRMEN1ALDH1A1 | |
| SCHEMBL4144564 | 0.76 | DNM1 (0.58) | DNM1KDM4ETSHRMEN1ALDH1A1 | |
| SCHEMBL16784070 | 0.76 | DNM1 (0.67) | DNM1TSHRMEN1ALDH1A1KMT2A | |
| SCHEMBL4401534 | 0.76 | DNM1 (0.67) | DNM1TSHRMEN1ALDH1A1KMT2A | |
| SCHEMBL1527147 | 0.75 | DNM1 (0.72) | DNM1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL27303955 | 0.75 | — | — | |
| SCHEMBL21611 | 0.74 | ZDHHC20 (0.58) | DNM1KDM4ETSHRMEN1ALDH1A1 | |
| SCHEMBL27790589 | 0.74 | ZDHHC20 (0.58) | DNM1KDM4ETSHRMEN1ALDH1A1 | |
| SCHEMBL29317564 | 0.74 | DNM1 (0.60) | DNM1KDM4ETSHRMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021137646-A1 | PYRROLOBENZODIAZEPINE DERIVATIVE AND LIGAND-LINKER CONJUGATE THEREOF | 주식회사 레고켐바이오사이언스 | 2021-07-08 | — | — | WO | disclosed |