SCHEMBL23627367

SCHEMBL23627367

Cc1cc(C(c2ccc(I)cc2)c2cc(C)c(OCCc3ccc(O)cc3)c(C)c2)cc(C)c1OCCc1ccc(O)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.40
SCN8A Q9UQD0 1/20 0.38
MMP10 P09238 1/20 0.35
MMP8 P22894 1/20 0.35
MMP13 P45452 1/20 0.35
ADRB2 P07550 2/20 0.33
LMNA P02545 2/20 0.33
SLC6A2 P23975 2/20 0.33
SLC6A4 P31645 2/20 0.33
OPRM1 P35372 2/20 0.33
CYP2D6 P10635 1/20 0.33
HIF1A Q16665 1/20 0.33
GALR3 O60755 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRA1A P35348 1/20 0.33
OPRK1 P41145 1/20 0.33
SLC6A3 Q01959 1/20 0.33
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
TYR P14679 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21775766 0.90 SCN8A (0.39) SCN8AMMP10MMP8MMP13ADRB2
SCHEMBL23627430 0.81 HTR1A (0.36)
SCHEMBL23627374 0.77 PCNA (0.39) APPESR1ESR2
SCHEMBL23627365 0.74 GCGR (0.30) APP
SCHEMBL23627376 0.73 APP (0.36) APP
SCHEMBL23627378 0.71 GAA (0.32) LMNA
SCHEMBL23627366 0.71 MAOA (0.33)
SCHEMBL21241741 0.70 PTGS1 (0.41) LMNAESR1ESR2
SCHEMBL23627369 0.70 ESR1 (0.46) APPLMNASLC6A2OPRM1CYP2D6
SCHEMBL23627375 0.69 ALDH1A1 (0.41) LMNAHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210206901-A1 COMPOUND, COMPOSITION CONTAINING THE SAME, METHOD FOR FORMING RESIST PATTERN AND METHOD FOR FORMING INSULATING FILM MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-07-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210206901-A1 COMPOUND, COMPOSITION CONTAINING THE SAME, METHOD FOR FORMING RESIST PATTERN AND METHOD FOR FORMING INSULATING FILM BMI1, PRDM9, CTCF APP 587/4885SCN8A 4548/4885MMP10 2326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.