Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CAD | P27708 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2362773 | 1.00 | HTT (0.39) | HTTCADALDH1A1 | |
| SCHEMBL1449554 | 0.79 | KMT2A (0.36) | HTTALDH1A1 | |
| SCHEMBL7455295 | 0.77 | HTT (0.46) | HTTCADALDH1A1 | |
| SCHEMBL7280583 | 0.75 | CREBBP (0.32) | ALDH1A1 | |
| SCHEMBL17048706 | 0.75 | CREBBP (0.32) | ALDH1A1 | |
| SCHEMBL8880745 | 0.75 | CREBBP (0.32) | ALDH1A1 | |
| SCHEMBL25414095 | 0.67 | HTT (0.46) | HTTCAD | |
| SCHEMBL1973599 | 0.67 | HTT (0.55) | HTTCAD | |
| SCHEMBL7551520 | 0.67 | HTT (0.46) | HTTCAD | |
| SCHEMBL19585894 | 0.67 | HTT (0.46) | HTTCAD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394970-B2 | Process for manufacturing a glutamic acid derivative and a pyroglutamic acid derivative and a novel intermediate in the manufacture thereof | AJINOMOTO CO., INC. (JP) | 2013-03-12 | — | — | US | disclosed |
| EP-1582514-B1 | PROCESSES FOR PRODUCING GLUTAMIC ACID DERIVATIVE, A PYROGLUTAMIC ACID DERIVATIVE AND A NOVEL INTERMEDIATE FOR PRODUCTION | AJINOMOTO KK (JP) | 2011-08-31 | — | — | EP | disclosed |
| US-7674915-B2 | Process for manufacturing a glutamic acid derivative and a pyroglutamic acid derivative and a novel intermediate in the manufacture thereof | AJINOMOTO CO., INC. (JP) | 2010-03-09 | — | — | US | disclosed |
| US-20100010234-A1 | PROCESS FOR MANUFACTURING A GLUTAMIC ACID DERIVATIVE AND A PYROGLUTAMIC ACID DERIVATIVE AND A NOVEL INTERMEDIATE IN THE MANUFACTURE THEREOF | AJINOMOTO CO. INC (JP) | 2010-01-14 | — | — | US | disclosed |
| US-20060009394-A1 | Process for manufacturing a glutamic acid derivative and a pyroglutamic acid derivative and a novel intermediate in the manufacture thereof | AJINOMOTO CO. INC (JP) | 2006-01-12 | — | — | US | disclosed |
| EP-1582514-A1 | PROCESSES FOR PRODUCING GLUTAMIC ACID DERIVATIVE AND PYROGLUTAMIC ACID DERIVATIVE AND NOVEL INTERMEDIATE FOR PRODUCTION | Ajinomoto Co., Inc. (JP) | 2005-10-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100010234-A1 | PROCESS FOR MANUFACTURING A GLUTAMIC ACID DERIVATIVE AND A PYROGLUTAMIC ACID DERIVATIVE AND A NOVEL INTERMEDIATE IN THE MANUFACTURE THEREOF | PTMA, GRIK5, GLUL | HTT 861/4885CAD 2574/4885ALDH1A1 1297/4885 |
| US-20060009394-A1 | Process for manufacturing a glutamic acid derivative and a pyroglutamic acid derivative and a novel intermediate in the manufacture thereof | PTMA, GRIK5, GLUL | HTT 861/4885CAD 2574/4885ALDH1A1 1297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.