Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17048706 | 1.00 | CREBBP (0.32) | CREBBPALDH1A1 | |
| SCHEMBL8880745 | 1.00 | CREBBP (0.32) | CREBBPALDH1A1 | |
| SCHEMBL7282521 | 0.80 | ALDH1A1 (0.33) | CREBBPALDH1A1 | |
| SCHEMBL21552614 | 0.77 | PRKCA (0.35) | CREBBP | |
| SCHEMBL21552617 | 0.77 | PRKCA (0.35) | CREBBP | |
| SCHEMBL2362771 | 0.75 | HTT (0.39) | ALDH1A1 | |
| SCHEMBL2362773 | 0.75 | HTT (0.39) | ALDH1A1 | |
| SCHEMBL8880607 | 0.74 | — | — | |
| SCHEMBL7281683 | 0.74 | — | — | |
| SCHEMBL209722 | 0.68 | CREBBP (0.36) | CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |